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Clinical History:
63 year-old male with end stage non ischemic
cardiomyopathy and severe heart failure underwent a
heart transplant.
Histology: The above histological sections of
myocardial tissue show multiple foci of mixed
inflammation, interstitial fibrosis and occasional
myocardial necrosis. The infiltrates are comprised of
lymphocytes, macrophages, eosinophils, plasma cells,
histiocytic aggregates and giant cells (arrow in figure
A). Trichrome stain (Figure E) highlights the
interstitial myocardial fibrosis. |
