Clinical History: 45 year-old male with
history of pulmonary sarcoidosis, atrial flutter and non
ischemic dilated cardiomyopathy.
Histology: H&E
sections of
heart explant show various discrete, non necrotizing
granulomas that are composed of nodular lesions with epithelioid histiocytes,
mononuclear cells, fibroblasts and multinucleated giant
cells (arrow in figure E. There is no myocyte necrosis
ruling out giant cell myocarditis. |