Coronary Allograft Vasculopathy

Figure A: Gross

Figure B: H&E stain 20x

Figure C: H&E stain 40x

Figure D: H&E stain 40x

Figure E: H&E stain 20x




Clinical History: 54 year-old male with history of non-ischemic cardiomyopathy; he received a heart allograft 5 years ago. He had sudden death with no previous evidence of cardiac insufficiency.

Histology: H&E staining (Figures B - E) show histological images of sections of coronary arteries showing Coronary Allograft Vasculopathy of a heart transplant recipient at different magnifications. Coronary arteries show marked concentric intimal thickening. Figure D is a higher magnification image of a section of Figure C showing the presence of foamy macrophages.

Gross : Gross appearance of coronary artery at autopsy (Figure A). 

(Last Edition: December 13, 2019 )