Coronary Allograft Vasculopathy

Figure A: Gross

Figure B: H&E stain 20x

Figure C: H&E stain 40x

Figure D: H&E stain 40x

Figure E: H&E stain 20x




Clinical History: 54 year old male with history of non-ischemic cardiomyopathy; he received a heart allograft 5 years ago. He had sudden death with no previous evidence of cardiac insufficiency.

Figure A: Gross appearance of coronary artery at autopsy.

Figures B - E: Histological images of sections of coronary arteries showing Coronary Allograft Vasculopathy of a heart transplant recipient at different magnifications. Coronary arteries show marked concentric intimal thickening. Figure D is a higher magnification image of a section of Figure C showing the presence of foamy macrophages.

(Last Edition: March 17, 2018 )